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595,596 Recent studies have demonstrated that itaconate derivative 4-octyl itaconate (OI) also inhibits glycolysis and exerts anti-inflammatory effects by targeting glyceraldehyde 3-phosphate dehydrogenase (GAPDH)

We have identified a family of chloroacetamide-containing compounds with potent inhibitory activity against GSTO1 and efficacy against cancer cells in both in vitro and in vivo models

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In the future, more prospective randomized controlled clinical studies can be conducted for patients with diabetic obesity or simple obesity

L-carnitine, on the other hand, may combine with organic acids to form water-soluble metabolites and promote their excretion [52]

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